Palbociclib 75mg Capsules

Palbociclib 75mg Capsules is a targeted therapy medication used primarily to treat specific types of advanced or metastatic breast cancer.

• Indication: Used for HR-positive, HER2-negative advanced or metastatic breast cancer.
• Combination Therapy: It is almost always prescribed alongside hormonal therapies such as letrozole, anastrozole, exemestane, or fulvestrant.
• How it Works: It is a CDK4/6 inhibitor. It blocks specific proteins (cyclin-dependent kinases 4 and 6) that signal cancer cells to grow and divide.
• Usage Instructions
  • • Schedule: Typically taken once daily for 21 consecutive days, followed by a 7-day break.
    • Administration:
      • • With Food: Capsules should be taken with food at approximately the same time each day to ensure consistent absorption.
        • Whole Swallow: Do not open, chew, or crush the capsules. If a capsule is broken or cracked, do not use it.
        • Missed Dose: If you vomit or miss a dose, do not take an extra dose. Simply wait for your next scheduled time. [1, 2, 3, 4, 5]

  Key Precautions & Side Effects
  • Blood Monitoring: Regular blood tests are required to check for neutropenia (low white blood cell count), which increases infection risk.
  • Interactions: Avoid grapefruit and grapefruit juice, as well as St. John’s Wort, as they can interfere with how the drug is processed.
  • Common Side Effects: Fatigue, hair thinning/loss, nausea, diarrhea, decreased appetite, and mouth sores.
  • Birth Control: Both men and women must use effective contraception during and for several weeks after treatment (3 weeks for women, 14 weeks for men) due to risks to a developing foetus.