Abiraterone acetate tablets are a prescription hormonal therapy used primarily to treat advanced prostate cancer that has spread to other parts of the body. [1, 2]
Key Usage & Administration
- Purpose: It works by decreasing the production of androgens (male hormones like testosterone) that fuel the growth of prostate cancer cells.
- Combination Therapy: It is almost always prescribed alongside a steroid, such as prednisone or prednisolone, to reduce the risk of side effects like high blood pressure, fluid retention, or low potassium levels.
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1. Product Overview
- Active Ingredient: Abiraterone Acetate
- Strength: 250 mg per tablet
- Therapeutic Class: Androgen biosynthesis inhibitor (CYP17 inhibitor)
- Indication: Primarily used for treating metastatic castration-resistant prostate cancer (mCRPC) and metastatic high-risk castration-sensitive prostate cancer (mCSPC), typically in combination with a corticosteroid like prednisone.
- 2. Dosage & Administration
- Standard Dose: The recommended dose is 1,000 mg (four 250 mg tablets) taken orally once daily.
- Empty Stomach Rule: Must be taken on an empty stomach. No food should be consumed for at least 2 hours before and 1 hour after the dose.
- Concomitant Therapy: Must be taken with prednisone or prednisolone (usually 5 mg twice daily or 5 mg once daily, depending on the condition).
- Whole Tablet: Tablets must be swallowed whole with water; do not crush, chew, or split them






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